Pierre Schiller writes:
There is a lot of potential when you combine 2D illustrations with the manga style and 3D volumes inside Blender. One such obvious advantage is that you can plan how to 3D sculpt your model's face. Similarly you can also plan how much framing of the face of the character you'd use in a panel, or quickly do different composites using your sketched facial features from your character to get dramatic angles with the camera FOV.
Given that you are truly using a 3D camera and all its properties, combined with Blender's realtime viewport, the possibilities to create stylized manga volume illustrations are great!
Check out the blog post including shortcuts and the making-of video